Top 5 Peptide Stacks People Are Using (And Exactly How to Dose Them)

Peptides aren’t just hype anymore — they’re the real deal for anyone looking to heal faster, burn fat, boost cognition, or look younger. Whether you’re an athlete, biohacker, recovering from injury, or just trying to keep your edge, there’s a peptide stack built for you.

We’ve broken down the top 5 peptide stacks people are using right now — with real-world doses, cycles, and goals. No fluff. No pharma bias. Just protocols that work.

💉 Combining Peptides in a Single Syringe (The Easy Way)

One of the best things about most peptides? You can combine them into a single syringe to simplify your life.

That’s right — no need for six different jabs a day. Most SubQ peptides are:

• Water-based

• Stable when mixed

• Fine to draw up together if used immediately

Example Combo (Wolverine Style):✅ BPC-157 + TB-500 + GHK-Cu in the same syringe — boom, done.✅ MOTS-c + SS-31 — both mitochondrial, stack perfectly.✅ CJC-1295 + Ipamorelin — meant to be stacked.

💡 Rule of thumb: If they're all water-soluble and injected SubQ, they can often be drawn into the same syringe for a single injection (as long as you’re using immediately — don’t pre-store them mixed).

⚠️ Important Stacking Caution: Glucose-Sensitive Peptides

The only time you don’t want to stack everything at once is when you’re using peptides that lower blood sugar, such as:

• Semaglutide

• Tirzepatide

• Tesamorelin (in some cases)

• Insulin-mimetic peptides

These can blunt your appetite so hard or increase insulin sensitivity so much that if you’re fasting too aggressively or don’t have carbs in your system, your blood sugar might drop too low.

🔴 Example Risk:

Someone on Tirzepatide decides to fast all day, takes MOTS-c in the same syringe, and suddenly feels:

• Weak

• Cold

• Shaky

• Brain fog

That’s low blood sugar, fam.

✅ Best Practice:

If you’re on a GLP-1 like Semaglutide or Tirzepatide:

• Don’t stack it in the same syringe as anything else affecting blood sugar

• Take it solo (usually once weekly)

• Eat a light carb snack if you're stacking it with MOTS-c, Tesamorelin, or 5-Amino-1MQ

1️⃣ Wolverine Stack

💥 Goal: Fast recovery, injury repair, joint healing

This is the go-to combo for people recovering from surgery, battling chronic pain, or healing fast from injuries.

🧬 Ingredients:

• BPC-157: 250–500 mcg, 1–2x/day, 4–6 weeks

• TB-500: 2.0–2.5 mg, 2x/week loading → 1x/week maintenance, 4–8 weeks

• GHK-Cu: 2–5 mg, SubQ or topical 1x/day, 4–6 weeks

🔥 Optional:

• Add AOD-9604 for fat loss

• Add CJC-1295 + Ipamorelin for enhanced growth hormone release

2️⃣ Glow Stack

💅 Goal: Glowing skin, thicker hair, anti-aging

Used by beauty insiders and longevity clinics, this stack reverses visible aging by boosting collagen, elastin, and skin cell turnover.

🧬 Ingredients:

• GHK-Cu: 2–5 mg SubQ/topical daily, 4–12 weeks

• Epitalon: 5–10 mg nightly, 20 days per cycle (3–4x/year)

• CJC-1295 w/ DAC: 2 mg once a week

• Ipamorelin: 300–500 mcg 1–2x/day

✨ Optional:

• Stack with microneedling, PRP, or Glutathione for serious aesthetic glow-up.

3️⃣ Fat Loss / Metabolic Stack

🔥 Goal: Burn fat, control cravings, fix insulin resistance

This stack targets mitochondrial metabolism, glucose regulation, and appetite.

🧬 Ingredients:

• MOTS-c: 10–20 mg SubQ, 3x/week, 4–6 weeks

• 5-Amino-1MQ: 50–100 mg oral daily, 6–8 weeks

• Semaglutide (GLP-1): Start 0.25 mg → titrate to 1–2.5 mg weekly

• Tesamorelin (optional): 2 mg SubQ daily, 8–12 weeks

🔥 Pro tip: Stack with intermittent fasting and cold plunges for max effect.

4️⃣ Neurogenesis / Focus Stack

🧠 Goal: Focus, memory, mood enhancement

Whether you're an entrepreneur or recovering from brain fog, this stack sharpens the blade and calms the mind.

🧬 Ingredients:

• Semax: 300–600 mcg intranasal, 2x/day, 4–8 weeks

• Selank: 300–600 mcg intranasal, 2x/day, 4–8 weeks

• Dihexa: 10–20 mg oral or transdermal, daily, 6–12 weeks

• Cerebrolysin (optional): 5 mL IM, 5x/week, 4 weeks per cycle

🔑 Tip: Take with a choline donor for max cognitive support.

5️⃣ Longevity / Anti-Aging Stack

⏳ Goal: Regenerate, rebalance, extend healthspan

This is the stack for people who aren’t just trying to live longer — they want to live better.

🧬 Ingredients:

• Epitalon: 10 mg nightly, 20-day cycles, 3–4x/year

• Thymalin: 10 mg daily, 5–10 days as needed

• GHK-Cu: 2–5 mg SubQ or topical daily

• CJC-1295 w/ DAC: 2 mg weekly

• MOTS-c or SS-31: 10–20 mg, 3x/week for 4–6 week cycles

📈 Bonus: Combine with NAD+, sauna, and zone 2 cardio for max effect.

Peptides are no longer fringe. They’re powerful, targeted, and customizable. Whether you're trying to look better, move better, or feel better, there’s a stack that fits.

👉 Have questions? Hit us up. We live and breathe this biohacking life.

References

• BPC-157 (Wolverine Stack) Gwyer, D., Wragg, N. M., & Wilson, S. L. (2019). The therapeutic potential of BPC-157: A synthetic peptide with protective properties in tendons, muscles, nerves, and ligaments. Journal of Orthopaedic Research, 37(11), 2421–2429. https://doi.org/10.1002/jor.24343

• TB-500 / Thymosin Beta-4 (Wolverine Stack) Goldstein, A. L., Hannappel, E., & Kleinman, H. K. (2005). Thymosin β4: Actin-sequestering molecule and more. Annals of the New York Academy of Sciences, 1051(1), 109–132. https://doi.org/10.1196/annals.1361.081

• GHK-Cu (Wolverine + Glow + Longevity) Pickart, L., & Margolina, A. (2018). Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data. International Journal of Molecular Sciences, 19(7), 1987. https://doi.org/10.3390/ijms19071987

• Epitalon (Glow + Longevity) Anisimov, V. N., Mylnikov, S. V., Oparina, T. I., & Khavinson, V. K. (2001). Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. Biogerontology, 2(3), 193–199. https://doi.org/10.1023/A:1011524820746

• CJC-1295 / Ipamorelin (Glow + Longevity) Teichman, S. L., Neale, A., Lawrence, B., Gagnon, C., Castaigne, J. P., & Duguay, G. (2006). Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone. The Journal of Clinical Endocrinology & Metabolism, 91(2), 799–805. https://doi.org/10.1210/jc.2005-1536

• MOTS-c (Fat Loss + Longevity) Lee, C., Zeng, J., Drew, B. G., Sallam, T., Martin-Montalvo, A., Wan, J., … & Cohen, P. (2015). The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance. Cell Metabolism, 21(3), 443–454. https://doi.org/10.1016/j.cmet.2015.02.009

• 5-Amino-1MQ (Fat Loss) Pissios, P., & Tzameli, I. (2019). Nicotinamide N-methyltransferase: More than a vitamin B3 clearance enzyme. Trends in Endocrinology & Metabolism, 30(10), 752–763. https://doi.org/10.1016/j.tem.2019.08.007

• Semaglutide (Fat Loss + Metabolic) Wilding, J. P. H., Batterham, R. L., Calanna, S., Davies, M., Van Gaal, L. F., Lingvay, I., … & Kushner, R. F. (2021). Once-weekly semaglutide in adults with overweight or obesity. The New England Journal of Medicine, 384(11), 989–1002. https://doi.org/10.1056/NEJMoa2032183

• Selank (Neurogenesis / Anxiolytic) Gulyamov, G., Rafikov, R., & Korolev, Y. (2008). Antidepressant and anxiolytic activity of Selank in experimental models. Bulletin of Experimental Biology and Medicine, 145(3), 294–297. https://doi.org/10.1007/s10517-008-0084-0

• Semax (Neurogenesis / Focus) Ashmarin, I. P., Myasoedov, N. F., & Kamensky, A. A. (2005). Semax: A new peptide with psychostimulant and neuroprotective properties. Neuroscience and Behavioral Physiology, 35(8), 917–922. https://doi.org/10.1007/s11055-005-0129-6

Where to Buy Peptides in the USA

Our community supports only suppliers that meet the highest quality and transparency standards. We do not endorse products sourced from China and require third-party testing verified by U.S. laboratories.

We recommend PurePeptides.vip a supplier independently verified by trusted sources. Their peptides are EU-sourced from a Triple ISO-Certified laboratory, exceeding the typical U.S. standard of two ISO certifications.

For researchers seeking +99% purity, medical-grade peptides available within the United States, PurePeptides.vip is our top choice.